50 Most Important NEET PYQs of Chapter 10: Cell Cycle and Cell Division – Part 1 (Q1–25) | By neetpyqall

 🧬 50 Most Important NEET PYQs of Chapter 10: Cell Cycle and Cell Division – Part 1 (Q1–25) | By neetpyqall

Let's dive into the first 25 most important and frequently asked NEET questions from Chapter 10 – Cell Cycle and Cell Division, along with clear, easy-to-understand solutions. This will help you revise smart and score sharp! ✅


1. What is the phase of the cell cycle where DNA replication occurs?

A) G1 phase
B) G2 phase
C) S phase
D) M phase
Answer: C) S phase
📘 Explanation: The S or synthesis phase is when the DNA is replicated, doubling the DNA content of the cell.


2. Which stage of mitosis is characterized by the alignment of chromosomes at the equator?

A) Prophase
B) Metaphase
C) Anaphase
D) Telophase
Answer: B) Metaphase
📘 Explanation: During metaphase, chromosomes line up at the metaphase plate (cell’s equator), attached to spindle fibers.


3. Synapsis occurs during:

A) Metaphase I
B) Prophase I
C) Anaphase I
D) Telophase I
Answer: B) Prophase I
📘 Explanation: Synapsis, or pairing of homologous chromosomes, is a key feature of prophase I in meiosis.


4. The cell cycle is regulated by:

A) Ribosomes
B) Cyclins and CDKs
C) Lysosomes
D) Mitochondria
Answer: B) Cyclins and CDKs
📘 Explanation: Cyclins and Cyclin-dependent kinases (CDKs) control the progression of cells through the cell cycle.


5. Which of the following is not a part of interphase?

A) G0 phase
B) G1 phase
C) S phase
D) M phase
Answer: D) M phase
📘 Explanation: The M phase (mitotic phase) is separate from interphase, which includes G1, S, and G2 phases.


6. What is the diploid number of chromosomes in humans?

A) 23
B) 46
C) 92
D) 69
Answer: B) 46
📘 Explanation: Humans have 46 chromosomes (23 pairs), making them diploid.


7. Crossing over occurs during:

A) Zygotene
B) Pachytene
C) Diplotene
D) Diakinesis
Answer: B) Pachytene
📘 Explanation: During the pachytene stage of prophase I, homologous chromosomes exchange genetic material via crossing over.


8. The structure that holds sister chromatids together is:

A) Centrosome
B) Chromatin
C) Centromere
D) Spindle fiber
Answer: C) Centromere
📘 Explanation: The centromere holds sister chromatids together until they are pulled apart during anaphase.


9. Which phase of mitosis follows metaphase?

A) Anaphase
B) Prophase
C) Telophase
D) Interphase
Answer: A) Anaphase
📘 Explanation: In anaphase, sister chromatids are separated and pulled toward opposite poles.


10. In meiosis, the number of chromosomes is reduced to half during:

A) Meiosis I
B) Meiosis II
C) Mitosis
D) Interphase
Answer: A) Meiosis I
📘 Explanation: Meiosis I is the reductional division where homologous chromosomes are separated.


11. Karyokinesis refers to:

A) Division of nucleus
B) Division of cytoplasm
C) DNA replication
D) Formation of spindle
Answer: A) Division of nucleus
📘 Explanation: Karyokinesis is nuclear division; cytokinesis is the division of the cytoplasm.


12. How many mitotic divisions are needed to produce 128 cells from a single cell?

A) 64
B) 127
C) 7
D) 128
Answer: C) 7
📘 Explanation: 2⁷ = 128, so 7 mitotic divisions are needed.


13. The point where crossing over occurs is called:

A) Centromere
B) Chromatid
C) Chiasma
D) Spindle
Answer: C) Chiasma
📘 Explanation: Chiasmata are the visible sites of crossing over between homologous chromosomes.


14. During mitosis, spindle fibers attach to chromosomes at:

A) Centromere
B) Centrosome
C) Kinetochores
D) Chromatid
Answer: C) Kinetochores
📘 Explanation: Spindle fibers attach to kinetochores, specialized structures on centromeres.


15. Which of the following occurs in anaphase I of meiosis?

A) Separation of chromatids
B) Separation of homologous chromosomes
C) Duplication of chromosomes
D) Synthesis of spindle fibers
Answer: B) Separation of homologous chromosomes
📘 Explanation: Homologous chromosomes (not chromatids) are pulled apart in anaphase I.


16. G0 phase is characterized by:

A) DNA replication
B) Cell division
C) Quiescent stage
D) Cytokinesis
Answer: C) Quiescent stage
📘 Explanation: G0 is a resting phase where cells are metabolically active but not dividing.


17. Centrioles duplicate in which phase of the cell cycle?

A) G1
B) S phase
C) G2 phase
D) M phase
Answer: B) S phase
📘 Explanation: Along with DNA replication, centrioles also duplicate during the S phase.


18. Cell plate formation is a characteristic of:

A) Cytokinesis in animal cells
B) Cytokinesis in plant cells
C) Prophase
D) Anaphase
Answer: B) Cytokinesis in plant cells
📘 Explanation: In plant cells, the cell plate forms between daughter nuclei and develops into a new cell wall.


19. What is the function of spindle fibers?

A) Attach chromatids to centromeres
B) Help in cell growth
C) Move chromosomes during division
D) Duplicate chromosomes
Answer: C) Move chromosomes during division
📘 Explanation: Spindle fibers pull chromosomes toward the poles during anaphase.


20. The nuclear envelope reappears during:

A) Prophase
B) Metaphase
C) Anaphase
D) Telophase
Answer: D) Telophase
📘 Explanation: In telophase, the nuclear membrane reforms around each set of chromosomes.


21. Leptotene is a stage of:

A) Prophase I
B) Anaphase II
C) Metaphase I
D) Telophase I
Answer: A) Prophase I
📘 Explanation: Leptotene is the first sub-stage of prophase I in meiosis.


22. How many chromatids are present in a human cell at the end of S phase?

A) 23
B) 46
C) 92
D) 69
Answer: C) 92
📘 Explanation: After DNA replication, each of the 46 chromosomes has two chromatids: 46 × 2 = 92.


23. What marks the end of prophase?

A) DNA replication
B) Disappearance of nuclear envelope
C) Chromosome condensation
D) Spindle formation
Answer: B) Disappearance of nuclear envelope
📘 Explanation: The breakdown of the nuclear envelope signals the transition from prophase to metaphase.


24. The duration of cell cycle is longest in:

A) G1 phase
B) S phase
C) M phase
D) G2 phase
Answer: A) G1 phase
📘 Explanation: G1 is usually the longest phase where the cell grows and prepares for DNA replication.


25. In animal cells, cytokinesis is achieved by:

A) Cell plate formation
B) Furrow formation
C) Spindle formation
D) Budding
Answer: B) Furrow formation
📘 Explanation: In animal cells, a cleavage furrow forms to divide the cytoplasm during cytokinesis.


🔜 Stay tuned for Part 2 (Q26–50) of Chapter 10!

📚 For complete NEET biology preparation, visit:
🔗 neetpyqall.blogspot.com
🔗 biologyatease1.blogspot.com


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